Our microfluidic technology and pre-optimized processes, your analysis and discovery

Take your research to the next level with Nadia

Automated, Standardized, Flexible

Challenge rigidity, empower creativity, and discover boundless curiosity. Nadia allows you to process any biological material with a wide range of predefined methods that is truly easy-to-use.


microfluidic steps
defined by us


up to 8 samples in parallel


results and answer your research questions

Nadia’s features

Nadia Instrument
Nadia Instrument

Ease of use

Fully automated sample encapsulation, detection of application-specific cartridges, with a touch screen interface and sample loading guide lights


Capable of processing 1, 2, 4 or 8 samples in parallel

Temperature control

Automated sample chilling to maintain transcriptome state or heating for hydrogel studies


Single use cartridge

Disposable cartridges with no wetted parts to avoid cross contamination


Truly single cell – ultra low cell doublet rates due to gentle cell agitation


The benefits of the Nadia Instrument

A controlled, reliable and reproducible microfluidic solution

Study biological processes at the cellular and molecular level

Sample compatibility

The Nadia Instrument can encapsulate biologicals up to 50 μm in diameter due to its wide chip junction size

Standardized protocols

Application specific protocols, workflows and consumables, such as cartridges and reagent kits

Sequencing agnostic

Library sequencing using short or long read sequencing technologies

High quality

The advantages of an enclosed, compact. microfluidic system, with high quality, monodisperse, measurable outputs 

Why would you choose a microfluidic solution?

Discover how microfluidics could revolutionize your application or research area

Microfluidic vs batch methods

Microfluidic tools give you the ability to create high throughput droplets using small volumes of reagents of several samples in parallel. They give more control over the mixing and temperature of fluids leading to a higher reproducibility of experiments.

Why the Nadia Instument?

With the Nadia Instrument users can:

  • Produce uniform droplet in a much more reproducible manner than mixing reagents using pipettes
  • Precisely manipulate small volumes of fluids, producing large numbers of individually contained reaction vessels in a short period time
  • Repeat the same reaction under the same conditions or perform separate experiments on the same sample in parallel
The impact on your research

You can do more experiments in a shorter time with higher reproducibility, reducing the amount of cost, time and resources required for biological research.

With Nadia researchers can follow pre-optimized processes, with standard protocols, or explore the versatile range of in-puts on our technology with ease, regardless of your level of knowledge in microfluidics.

I don’t think there is any other instrument that is so simple to use but with such a diverse range of applications

– Dr Thomas Osborne, Technical Applications Specialist, Do Bio

Nadia Instrument workflow

Sample input




Application areas

Droplet Genomics



Compatible reagent kits


The nadAROSE kit provides a simple, low-cost commercial solution for the encapsulation of single cells in individual agarose micro-scaffolds in a high throughput, reproducible manner on the Nadia instrument.

The nadAROSE kit is compatible with many downstream applications. The cell-containing agarose scaffolds are compatible with flow cytometry instruments and could also be used for cell-cell interaction studies, cell secretome studies or for microbiological cell culture.

The kit also provides the necessary reagents to release cells from their agarose scaffolds for further cell analysis or merging of workflows.



One solution to take you from cells to data.

With the RNAdia 2.0 kit for the Nadia Instrument, gain access to a hassle free, streamlined workflow, where you can create single cell and single nuclei libraries and analyse them, all in one place.

Single cell research doesn’t need to be a hassle.

The Nadia Instrument takes scRNA-Seq to the next level by using automation and flexibility to generate high quality reproducible single cell data at high throughput to assay tens of thousands of cells. Together with the RNAdia 2.0 reagent kit and its streamlined workflow, this becomes a low cost, high quality, complete workflow for single cell sequencing and single nuclei sequencing.

Learn more about Nadia

Download the RNAdia 2.0 datasheet

Download the Nadia brochure

Watch the webinar

Flexible End to End Single Cell Workflows


What is the maximum size of biological that can be run on the system?

Up to 50 µm in diameter can be used on the Nadia Instrument. We advise that particles do not exceed this size to avoid blockages.

How many samples can I run in parallel?

You can run from 1 to 8 samples in parallel.

Can I use a very small volume of my reagent?

Yes. The Nadia Instrument supports volumes as small as 100µl.

Do you sell beads/buffers/reagent kits?

Yes, please find our application specific reagent kits here

How long are droplets stable for?

Around a week at room temperature or two weeks at 4°C when kept in a sealed container to avoid evaporation.

Will the Do Bio systems carry out downstream processes such as PCR/Sequencing?

The Do Bio systems provide a solution for encapsulating single cells into droplets with/without beads. The Nadia Instrument, in combination with the RNAdia kit, generates a set of barcoded mRNA capture beads with mRNA attached, ready for downstream processing. The RNAdia kit provides the reagents for this downstream processing, from reverse transcription to sequencing library preparation.

If you have queries about the protocol downstream of the encapsulation process, please contact

Which sequencing platforms are compatible with single cell libraries from the Nadia instrument?

All single cell cDNA libraries prepared on the Nadia Instrument are fully compatible with short-read sequencing on Illumina and long-read sequencing on PacBio or Oxford Nanopore sequencing devices.

To enquire whether you can use the Nadia system with your cell types, contact our applications team at

Do you have a list of cell types that your system has been used with?
  • Mouse hybridoma
  • CHO
  • Human and Mouse B-cells
  • Human T-cells
  • Cardiomyocytes
  • Hepatocytes
  • Jurkat cells
  • HEK3T3
  • Endometrium
  • Yeast
  • Plant Protoplasts
  • Bacterial cells such as E.coli and Streptomyces
  • Nuclei
  • Genomic DNA
    and many more
Are the chips single-use consumables?

The Nadia Chip is a single-use consumables which is discarded after a run. 

How do I clean my Nadia Instrument?

The Nadia product family does not have wetted parts and therefore doesn’t require cleaning. Chips are one time use and are therefore disposed of after every experiment.

How do I know what products/consumables/accessories I need?

We are able to advise you and produce system quotes on products if you are unsure of what you need to run your application. Please contact us.

Will my cells work with your systems?

In most cases, yes, your cells will work with the system. Whether a cell is compatible or not is dependent on many things such as the size and fragility of the cells. Please contact our applications team at for a detailed list of cells that have been trialed in our Nadia product family.

What range of droplet sizes can you make on one chip?

Typically, 20% larger or smaller than the junction size (this is achieved by varying the pressure/flow rate). On the Nadia instrument, you can generate droplets between ~65µm and 100µm in diameter.

Can you change buffers and reagents that are used in the system?

Yes, the Nadia Instrument when combined with the Nadia Innovate is fully flexible, allowing the use of your own reagents and the development of applications.