Nadia Innovate
Revolutionize your research with Nadia Innovate, a complete microfluidic platform for exploring, developing, and scaling new ideas or pre-optimized processes
A hassle free, open platform, for all your research goals
Flexible, controlled, reliable
We are putting an end to complicated and tedious modular microfluidic systems.
Nadia Innovate is the first microfluidic tool that allows you to process any biological material with your method of your choice. Allowing for full flexibility, scalability, and ease-of-use.
Customize
parameters to create user-defined protocols and applications
Develop
new microfluidic based workflows
Discover
newly developed protocols by transferring them to the Nadia Instrument for scalable, high throughput, parallel operation
The benefits of the Nadia Innovate
Nadia Innovate uses the Nadia Instrument as the core pressure controller and provides a workstation for development and test of new protocols on a single Nadia chip. Once validated, the protocols can be uploaded and executed on the Nadia Instrument
Customizable
Open configurable system to develop new protocols and applications
Flexible PC software
Easy-to-use software to control the Nadia Innovate and create, change, test, and save new protocols
Easy process visualization
High-speed microscope and camera for real-time observation of droplet formation
Rapid protocol optimization
User-defined adjustment of droplet size, frequency, droplet components, temperature, and agitation
Scalable
Following optimization, experimental conditions can be transferred easily onto the Nadia Instrument with Nadia Innovate cartridges, running 1, 2, 4, or 8 samples in parallel for deployment
Drive your research with customization
Easy software-controlled adjustments of critical parameters
Why the Nadia Innovate?
Nadia Innovate has been designed specifically to meet the needs of researchers who want to develop and validate new protocols and applications using microfluidic tools. Regardless of the level of your microfluidic expertise, Nadia Innovate can open the door to boundless research goals.
Nadia Innovate vs standard modular microfluidic systems
Compared to standard modular microfluidics systems, Nadia Innovate is:
-
Convenient: Fewer consumable parts, no tubing!
-
Consistent: Single use chips – no PDMS.
- Controlled: Easy operation with semi-automated steps.
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Compact: An enclosed microfluidic system.
Temperature
Temperature control is essential in many biological applications, and requirements vary depending on experimental needs.
For example, whilst keeping a cell sample at cold temperature helps maintain the transcriptome state, the production of hydrogel beads with agarose requires heating to keep the agarose molten.
With Nadia Innovate and Nadia Go, control the temperature from 4 – 40°C at every step, from sample loading, to during the run, to post-run incubation temperature.
Time
Adapt pre – and post run incubation steps to suit your sample type.
Or change the duration of a run to process different sample input volumes, ranging from 100 to 250 µl.
Stirring
To ensure an even distribution of cells and beads (if using beads) in droplets throughout a run, it is crucial to keep both in suspension as they will otherwise settle at the bottom of their respective wells, resulting in higher doublet rates.
On the Nadia Innovate and Nadia Go, stirring of cells and beads can be controlled individually, and stirring speeds can be changed dependent on cell and/or bead densities and properties.
Pressure
Precise pressure control of 3 independent channels up to 1 bar to ensure flexibility and precision of droplet formation.
Adjust presures of individual inputs to achieve optimal droplet formation to suit the cell size, buffer composition and viscosity, or bead material of the experiment.
The Nadia Innovate is incredibly intuitive and easy to use. Its versatility has allowed us to optimize parameters to reduce droplet volumes, increase capture rates and ultimately concentrate the RNA. Together this has resulted in a better insight of gene expression in each cell.
– Dr. Christopher Sibley, Principal Investigator
at the School of Biological Sciences, Edinburgh, UK
Nadia Innovate workflow
→
Your idea
→
input
→
Optimize
→
Analysis
→
Discover
→
Scale
on Nadia
→
Publish
Learn more about Nadia Innovate
Read the blog
‘Customizing single cell research protocols with Nadia Innovate’
Watch
Introducing the Nadia Innovate