Nadia Go
Discovery at your fingertips
Power your research with Nadia Go
A compact and affordable microfluidic system
Solve the frustrations associated with cumbersome modular systems and open the pathway to development, regardless of your level of microfluidic expertise.
Customize
parameters to create user-defined protocols and applications
Develop
new microfluidic based workflows
Discover
the unlimited possibilities of an open platform, built for novel microfluidic research and custom genomics projects.
The benefits of Nadia Go
The Nadia Go was created for researchers interested in development who do not require the scalable production features of the Nadia Instrument. The Nadia Go offers the customizable parameters of the Nadia Innovate without the necessity of purchasing a Nadia Instrument alongside it.
What is Nadia Go?
Nadia Go is a standalone, compact microfluidic tool providing a workstation for development and test of new protocols on a single Nadia chip. Cells, proteins, mRNA, lipids and other particles can be encapsulated with a wide range of buffers depending on sample needs.
Nadia Go vs standard modular microfluidic systems
Compared to standard modular microfluidics systems, Nadia Go is:
- Convenient: Fewer consumable parts and no tubing!
- Consistent: Reliable, single use chips- no PDMS.
- Controlled: Easy operation with semi automated steps.
- Compact: An enclosed microfluidic system with a small footprint.
Flexible
Open configurable system to develop new protocols and applications
Rapid protocol optimization
User-defined adjustment of droplet size, frequency, droplet components, temperature, and agitation
Easy process visualization
High-speed microscope and camera for real-time observation of droplet formation
Flexible PC software
Easy-to-use software to control the Nadia Go and create, change, test, and save new protocols
Easy software-controlled adjustments of
critical parameters on the Nadia Go
Temperature
Temperature control is essential in many biological applications, and requirements vary depending on experimental needs.
For example, whilst keeping a cell sample at cold temperature helps maintain the transcriptome state, the production of hydrogel beads with agarose requires heating to keep the agarose molten.
With Nadia Innovate and Nadia Go, control the temperature from 4 – 40°C at every step, from sample loading, to during the run, to post-run incubation temperature.
Time
Adapt pre – and post run incubation steps to suit your sample type.
Or change the duration of a run to process different sample input volumes, ranging from 100 to 250 µl.
Stirring
To ensure an even distribution of cells and beads (if using beads) in droplets throughout a run, it is crucial to keep both in suspension as they will otherwise settle at the bottom of their respective wells, resulting in higher doublet rates.
On the Nadia Innovate and Nadia Go, stirring of cells and beads can be controlled individually, and stirring speeds can be changed dependent on cell and/or bead densities and properties.
Pressure
Precise pressure control of 3 independent channels up to 1 bar to ensure flexibility and precision of droplet formation.
Adjust presures of individual inputs to achieve optimal droplet formation to suit the cell size, buffer composition and viscosity, or bead material of the experiment.
We are developing novel single cell sequencing applications that go above and beyond standard scRNA-Seq methodologies. This has all been possible because of the Nadia system.
– Dr. Adam Cribbs, Group leader, Botnar research Centre, University of Oxford
Nadia Go workflow
→
Your idea
→
Sample input
→
Optimize
→
Discover
→
Analysis
→
Publish
Learn more about Nadia Go
Watch
The Nadia Go intro video
Download the Nadia Go flyer
Watch
Introducing the Nadia Innovate