Nadia Click Chips
Swappable microfluidic glass chips for the Nadia Innovate and Nadia Go
Do more with a click
Click, process, discover
The new Nadia Click Chip range expands the capabilities of the Nadia Innovate and Nadia Go. In addition to the standard Nadia Chips and cartridges, we now offer a range of microfluidic glass chips specifically designed to address the needs of particular application areas.
Our range of Nadia Click Chips
40μm FACS
Sortable Click Chip
LNP 2 Reagent Click Chip
(coming soon!)
Compatible instruments: the Nadia Innovate and Nadia Go
Nadia Innovate uses the Nadia Instrument as the core pressure controller and provides a workstation for development and test of new protocols for downstream production on the Nadia Instrument. The Nadia Go is a stand alone instrument, which enables the same customizable parameters as the Innovate, without downstream scalability.
The benefits of the Nadia Click Chips
on the Nadia Innovate or Nadia Go
Customizable
Open configurable system to develop new protocols and applications.
Now with an ever expanding range of swappable application specific microfluidic glass chips.
Flexible PC software
Easy-to-use software to control the Nadia Innovate and create, change, test, and save new protocols.
Easy process visualization
High-speed microscope and camera for real-time observation of droplet formation.
Rapid protocol optimization
User-defined adjustment of droplet size, frequency, droplet components, temperature, and agitation.
Drive your research with customization
Easy software-controlled adjustments of critical parameters
Temperature
Temperature control is essential in many biological applications, and requirements vary depending on experimental needs.
For example, keeping a cell sample at cold temperature helps maintain the transcriptome state, the production of hydrogel beads with agarose requires heating to keep the agarose molten.
With Nadia Innovate and Nadia Go, control the temperature from 4 – 40°C at every step, from sample loading, to during the run, to post-run incubation temperature.
Time
Adapt pre – and post run incubation steps to suit your sample type.
Or change the duration of a run to process different sample input volumes, ranging from 100 to 250 µl.
Stirring
To ensure an even distribution of cells and beads (if using beads) in droplets throughout a run, it is crucial to keep both in suspension as they will otherwise settle at the bottom of their respective wells, resulting in higher doublet rates.
On the Nadia Innovate and Nadia Go, stirring of cells and beads can be controlled individually, and stirring speeds can be changed dependent on cell and/or bead densities and properties.
Pressure
Precise pressure control of 3 independent channels up to 1 bar to ensure flexibility and precision of droplet formation.
Adjust presures of individual inputs to achieve optimal droplet formation to suit the cell size, buffer composition and viscosity, or bead material of the experiment.
40 μm FACS Sortable Click Chip
High quality FACS sortable hydrogel scaffolds are
just a click away
Easy to use microfluidic glass chips for
FACS sortable hydrogel scaffolds and droplet genomics
Using our world-leading expertise we have created a microfluidic solution specifically designed to make small droplets, in order to provide optimal conditions for hydrogel scaffold production and increase the efficiency of your droplet genomics workflows.
40 µm FACS Sortable Click Chip features:
- Compatible: smaller channels enable the production of hydrogel scaffolds that are compatible downstream with standard FACS instruments
- Sort by external cellular environment
- Easy to use: regardless of the level of your microfluidic expertise
- Flexible: explore droplet genomics, or hydrogel scaffold production
- Reusable: cost saving, multiple use glass microfluidic chips
FACS analysis of HEK cells encapsulated in <40 μm agarose scaffolds on BD FACS Aria III. Cytopainter green labelled cells with (inset) post sort green-fluorescent cell-containing agarose scaffolds.